The two clubs go head‑to‑head at the MCG on Saturday at 7.40pm.
Five players are out from Collingwood’s lineup.
One player is still rehabbing after a car crash left him unconscious in training.
North Melbourne’s VFL side overcame North’s youngsters in their recent encounter by 43 points.
That win has provided the seniors added belief.
Both clubs want a positive kickoff to the latter half of the season.